Publications tagged "zoonoses"

Identifying and prioritizing potential human-infecting viruses from their genome sequences

We describe a machine learning model that identifies candidate zoonoses using evolutionary signals of host range encoded in viral genomes. This allows identification of high-risk viruses immediately upon discovery, increasing both the feasibility and likelihood of downstream virological and ecological characterization and allowing for evidence-driven virus surveillance. More

Characterizing and evaluating the zoonotic potential of novel viruses discovered in vampire bats

A case study in evaluating the zoonotic potential of newly-discoved viruses using molecular sequencing data. We highlight the value of evaluating zoonotic potential beyond ad hoc consideration of phylogeny and provide surveillance recommendations for novel viruses in a wildlife host which has frequent contact with humans and domestic animals. More

Viral zoonotic risk is homogenous among taxonomic orders of mammalian and avian reservoir hosts

Do some reservoir groups (e.g. bats) produce more zoonotic viruses than others? By cataloguing the accepted reservoirs for 415 viruses associated with mammals and birds, we show that there is currently no evidence for the existence of any such special reservoir groups. Instead, groups containing more reservoir species are associated with more viruses, and proportionally more zoonotic viruses. More